1.1 Prasugrel in combination with aspirin is recommended as an option for preventing atherothrombotic events in people with acute coronary syndromes having percutaneous coronary intervention, only when:
immediate primary percutaneous coronary intervention for ST-segment-elevation myocardial infarction is necessary or
stent thrombosis has occurred during clopidogrel treatment or
the patient has diabetes mellitus.
1.2 People currently receiving prasugrel for treatment of acute coronary syndromes whose circumstances do not meet the criteria in 1.1 should have the option to continue therapy until they and their clinicians consider it appropriate to stop.