NHS Dudley Health Economy Medicines Formulary
Home > 4 Central nervous system > 4.10 Drugs used in substance dependence > 4.10.3 Opioid dependence > Drug misuse - naltrexone - NICE TAG TA115

Drug misuse - naltrexone - NICE TAG TA115

1.1 Naltrexone is recommended as a treatment option in detoxified formerly opioid-dependent people who are highly motivated to remain in an abstinence programme.

1.2 Naltrexone should only be administered under adequate supervision to people who have been fully informed of the potential adverse effects of treatment. It should be given as part of a programme of supportive care.

1.3 The effectiveness of naltrexone in preventing opioid misuse in people being treated should be reviewed regularly. Discontinuation of naltrexone treatment should be considered if there is evidence of such misuse.


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