NHS Dudley Health Economy Medicines Formulary
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8.1 Cytotoxic drugs

General Guidance
 

  • Methotrexate should be prescribed in the community on the recommendation of a consultant rheumatologist.
  • Changes to the dosage of methotrexate should only be made by consultant rheumatologists.
  • Methotrexate should be administered only once per week, it is never used daily.
  • This drug requires regular specific monitoring in order to reduce toxicity – such monitoring is mandatory.
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